Sir John Tooke has 30 years of experience as a consultant physician specialising in diabetes, endocrinology, vascular medicine and internal medicine with research experience (basic biomedical, experimental medicine, and applied health research including improvement science) recognised through Fellowship of the Academy of Medical Sciences. Sir John is a non-executive director of BUPA Chile and the main BUPA board, and chair of the Medical Advisory Council. He is also chair of Collaboration for the Advancement of Sustainable Medical Innovation (CASMI) UCL, and chaired the Oversight Group for the Academy of Medical Sciences project 'How we best use scientific evidence to judge the benefits and harms of medicines'. Sir John was head of the School of Life and Medical Sciences at University College London as Vice Provost (Health) and Academic Director of UCL Partners. He held a board position at the Francis Crick Institute (2011 -2015) and was a Member of the Council for Science & Technology (2011-2015) reporting to the UK Prime Minister.